Gallbladder inflammation is primarily indicated by which of the following symptoms?

Gallbladder inflammation, also known as cholecystitis, is primarily characterized by abdominal pain and fever. The pain typically manifests in the right upper quadrant of the abdomen and may radiate to the back or shoulder. Fever often accompanies the pain, indicating an inflammatory response in the body. This combination of symptoms is crucial for diagnosing gallbladder issues and helps differentiate cholecystitis from other gastrointestinal conditions.

Other symptoms associated with gallbladder inflammation can include nausea, vomiting, and possibly jaundice, but the hallmark signs are the abdominal pain and fever. This aligns with the physiological response of the body to inflammation, which includes localized pain and systemic reactions like fever.

The other choices do not primarily relate to gallbladder inflammation. Weight gain and excessive appetite are generally not symptoms of gallbladder issues. While jaundice can occur if there is a blockage in bile flow, it is not specific to inflammation of the gallbladder itself and does not occur in all cases of cholecystitis. Therefore, the presence of abdominal pain and fever is the most direct indicator of gallbladder inflammation.